FABIAN-variant 2026

Filter variants Score... Known TFBSs only Coordinates... Select...? Activating this checkbox highlights all variants grey (selected state). Click a variant to change the selection, then press Enter to keep the selected variants or Backspace to hide them. Uncheck to cancel.

Sort variants Binding loss Binding gain Coordinates Input

Filter models Same species only TFFMs PWMs Model source... Score...

Options Prefer TFFMs? When checked, the combined score is calculated using only TFFMs when both PWMs and TFFMs exist for the same transcription factor. Show heterodimers? When checked, heterodimer complexes (e.g., AHR::ARNT) are shown as separate rows instead of being merged into their component TFs. TFBS source... DL markers Show log Panel layout Reset view

INFO: Analysis submitted on 2026-06-09 at 14:15 UTC. Depending on the number of variants and models, INFO: the search can take several minutes to complete. Your project has a unique URL. You can close INFO: the browser now and return to this URL later: https://fabianapp.org/variant26/1781014523_35887 INFO: When your search results are available, this computation log will disappear. You can display INFO: it again by checking the 'Options > Show log' checkbox on the top menu. INFO: Results are retained on the server for 14 days, after which they are automatically deleted. INFO: You can also save the project or manually delete your results. PARM: api_priority yes PARM: dl_scoring yes PARM: genome GRCh38/hg38 PARM: heterodimer show PARM: mode single PARM: organism human PARM: single_variant 2:127418425T>C PARM: sources JASPAR-TFFM JASPAR-PWM HOCOMOCO PARM: tfs_custom_names HNF1A PARM: tfs_filter names PARM: via_api yes

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